⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13186512 | 1.00 | — | — | |
| SCHEMBL7620002 | 1.00 | — | — | |
| SCHEMBL2483160 | 0.86 | — | — | |
| SCHEMBL7620666 | 0.86 | — | — | |
| Tert-Butyl Formate SCHEMBL27710947 | 0.80 | TDP1 (0.42) | — | |
| SCHEMBL4467181 | 0.78 | CRBN (0.37) | — | |
| SCHEMBL2042295 | 0.78 | — | — | |
| SCHEMBL14827803 | 0.78 | — | — | |
| SCHEMBL25324431 | 0.77 | USP2 (0.32) | — | |
| SCHEMBL10726202 | 0.75 | OR51E2 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 392 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4423082-A1 | CCR6 RECEPTOR MODULATORS | Idorsia Pharmaceuticals Ltd (CH) | 2024-09-04 | — | — | EP | claimed |
| WO-2023072924-A1 | CCR6 RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-05-04 | — | — | WO | claimed |
| EP-3774310-A1 | METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES | Alcon Inc. (CH) | 2021-02-17 | — | — | EP | claimed |
| CN-107254026-A | Polymer and nano-gel material and its preparation and application | 庄臣及庄臣视力保护公司 | 2017-10-17 | — | — | CN | claimed |
| WO-2017012963-A1 | POLYMERIZABLE FATTY ACID-DERIVATIVE-MONOMERS WITH TERMINAL OLEFINIC DOUBLE BONDS, POLYMERS CONTAINING SAME MONOMERS, PRODUCTION AND USE THEREOF | BASF SE (DE) | 2017-01-26 | — | — | WO | claimed |
| US-20150024436-A1 | SAMPLE PREPARATION, PROCESSING AND ANALYSIS SYSTEMS | INTEGENX INC, (US) | 2015-01-22 | — | — | US | claimed |
| WO-2013130910-A1 | SAMPLE PREPARATION, PROCESSING AND ANALYSIS SYSTEMS | INTEGENX INC. (US) | 2013-09-06 | — | — | WO | claimed |
| US-7906556-B2 | Methods of treating amyloidosis using cyclopropyl derivative aspartyl protease inhibitors | ELAN PHARMACEUTICALS, INC. (US) | 2011-03-15 | — | — | US | claimed |
| US-7858642-B2 | Substituted hydroxyethylamine aspartyl protease inhibitors | ELAN PHARMACEUTICALS, INC. (US) | 2010-12-28 | — | — | US | claimed |
| EP-1638970-B1 | PYRID (2, 1-A) - ISOQUINOLINE DERIVATIVES AS DPP-IV INHIBITORS | HOFFMANN LA ROCHE (CH) | 2010-11-24 | — | — | EP | claimed |
| US-20050239832-A1 | Methods of treatment of amyloidosis using bi-cyclic aspartyl protease inhibitors | ELAN PHARMACEUTICALS, INC. | 2005-10-27 | — | — | US | claimed |
| US-20050239836-A1 | Substituted hydroxyethylamine aspartyl protease inhibitors | ELAN PHARMACEUTICALS, INC. | 2005-10-27 | — | — | US | claimed |
| WO-2005087714-A2 | METHODS OF TREATMENT OF AMYLOIDOSIS USING BI-CYCLIC ASPARTYL PROTEASE INHIBITORS | ELAN PHARMACEUTICALS, INC. (US) | 2005-09-22 | — | — | WO | claimed |
| WO-2005087751-A2 | SUBSTITUTED HYDROXYETHYLAMINE ASPARTYL PROTEASE INHIBITORS | ELAN PHARMACEUTICALS, INC. (US) | 2005-09-22 | — | — | WO | claimed |
| WO-2005070407-A1 | METHODS OF TREATMENT OF AMYLOIDOSIS USING ASPARTYL-PROTEASE INIHIBITORS | ELAN PHARMACEUTICALS, INC. (US) | 2005-08-04 | — | — | WO | claimed |
| WO-2005000848-A1 | PYRIDO` 2, 1-A - ISOQUINOLINE DERIVATIVES AS DPP-IV INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-01-06 | — | — | WO | claimed |
| US-20040259903-A1 | Pyrido [2,1-a] isoquinoline derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 2004-12-23 | — | — | US | claimed |
| EP-0366316-B1 | Melt-processible aromatic polyamides | DU PONT (US) | 1994-12-07 | — | — | EP | claimed |
| US-5066445-A | Recovery and melt extrusion of aromatic/aliphatic copolyamides from lactam-plasticized polymer | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-11-19 | — | — | US | claimed |
| EP-0366316-A1 | Melt-processible aromatic polyamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-05-02 | — | — | EP | claimed |