Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 7/20 | 0.89 |
| ▸ | TERT | O14746 | 3/20 | 0.67 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.67 |
| ▸ | PPARG | P37231 | 3/20 | 0.67 |
| ▸ | PPARD | Q03181 | 3/20 | 0.67 |
| ▸ | PPARA | Q07869 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | BLM | P54132 | 2/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | FABP4 | P15090 | 2/20 | 0.67 |
| ▸ | GMNN | O75496 | 1/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | APEX1 | P27695 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oleic Acid SCHEMBL1203365 | 0.98 | FABP3 (0.92) | FABP3TERTPTPN1PPARGPPARD | |
| Oleic Acid SCHEMBL28038890 | 0.96 | FABP3 (0.89) | FABP3TERTPTPN1PPARGPPARD | |
| Oleic Acid SCHEMBL3173379 | 0.96 | FABP3 (0.89) | FABP3TERTPTPN1PPARGPPARD | |
| Palmitoleic Acid SCHEMBL2408219 | 0.96 | FABP3 (0.96) | FABP3TERTPTPN1PPARGPPARD | |
| Nervonic Acid SCHEMBL31621477 | 0.96 | FABP3 (0.96) | FABP3TERTPTPN1PPARGPPARD | |
| Oleic Acid SCHEMBL5979254 | 0.96 | FABP3 (0.96) | FABP3TERTPTPN1PPARGPPARD | |
| Oleic Acid SCHEMBL35214 | 0.96 | FABP3 (0.96) | FABP3TERTPTPN1PPARGPPARD | |
| Erucic Acid SCHEMBL30876194 | 0.96 | FABP3 (0.96) | FABP3TERTPTPN1PPARGPPARD | |
| Oleic Acid SCHEMBL35217 | 0.96 | FABP3 (0.96) | FABP3TERTPTPN1PPARGPPARD | |
| Oleic Acid SCHEMBL15811776 | 0.96 | FABP3 (0.96) | FABP3TERTPTPN1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1802427-B | Lubricant compositions containing an overbased amorphous alkaline earth metal salt as a metal protectant | OMG AMERICAS INC | 2010-08-04 | — | — | CN | disclosed |
| EP-1599437-B1 | POWDERED OVERBASED AMORPHOUS ALKALINE EARTH METAL SALTS AND PROCESSES FOR MAKING | OMG AMERICAS INC (US) | 2010-03-03 | — | — | EP | disclosed |
| US-7163912-B2 | Lubricant compositions containing an overbased amorphous alkaline earth metal salt as a metal protectant | OMG AMERICAS, INC. (US) | 2007-01-16 | — | — | US | disclosed |
| CN-1863759-A | Powdered overbased amorphous alkaline earth metal salts and processes for making | OMG AMERICAS INC (US) | 2006-11-15 | — | — | CN | disclosed |
| CN-1802427-A | Lubricant compositions containing an overbased amorphous alkaline earth metal salt as a metal protectant | OMG AMERICAS INC (US) | 2006-07-12 | — | — | CN | disclosed |
| EP-1603997-A2 | LUBRICANT COMPOSITIONS CONTAINING AN OVERBASED AMORPHOUS ALKALINE EARTH METAL SALT AS A METAL PROTECTANT | OMG Americas, Inc. (US) | 2005-12-14 | — | — | EP | disclosed |
| EP-1599437-A1 | POWDERED OVERBASED AMORPHOUS ALKALINE EARTH METAL SALTS AND PROCESSES FOR MAKING | OMG Americas, Inc. (US) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004078694-A1 | POWDERED OVERBASED AMORPHOUS ALKALINE EARTH METAL SALTS AND PROCESSES FOR MAKING | OMG AMERICAS, INC. (US) | 2004-09-16 | — | — | WO | disclosed |
| WO-2004078849-A2 | LUBRICANT COMPOSITIONS CONTAINING AN OVERBASED AMORPHOUS ALKALINE EARTH METAL SALT AS A METAL PROTECTANT | OMG AMERICAS, INC. (US) | 2004-09-16 | — | — | WO | disclosed |
| US-20040063589-A1 | Lubricant compositions containing an overbased amorphous alkaline earth metal salt as a metal protectant | OMG AMERICAS, INC. | 2004-04-01 | — | — | US | disclosed |
| US-6639090-B2 | For use in polymer stabilizers, lubricants, catalysts, oil well formulations, animal nutrition and cosmetics | OMG AMERICAS, INC. | 2003-10-28 | — | — | US | disclosed |
| US-20030158054-A1 | Powdered overbased amorphous alkaline earth metal salts and processes for making | OMG AMERICAS, INC. | 2003-08-21 | — | — | US | disclosed |