SCHEMBL316341

SCHEMBL316341

CC(C)N(C(=O)O)N(C(=O)O)C(C)C

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.39
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
SLC7A5 Q01650 1/20 0.32
FFAR3 O14843 1/20 0.31
LCK P06239 1/20 0.31
FYN P06241 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21788102 0.71 TSHR (0.33) TP53FFAR3LCKFYN
SCHEMBL6249962 0.71 TP53 (0.39) TP53MEN1KMT2ASLC7A5FFAR3
SCHEMBL42467 0.71 TP53 (0.39) TP53MEN1KMT2ASLC7A5FFAR3
SCHEMBL8593198 0.69
SCHEMBL638833 0.69 TP53 (0.37) TP53MEN1KMT2ASLC7A5
SCHEMBL22199559 0.69 TP53 (0.30) TP53
SCHEMBL968744 0.69
SCHEMBL1494555 0.69
SCHEMBL672963 0.69 TP53 (0.37) TP53MEN1KMT2ASLC7A5
SCHEMBL673528 0.69 TP53 (0.37) TP53MEN1KMT2ASLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 348 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1877513-B1 CAP LINERS, CLOSURES AND GASKETS FROM MULTI-BLOCK POLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2019-05-08 EP claimed
US-20180222909-A1 PROCESS FOR THE PREPARATION OF IBRUTINIB AND NEW SYNTHESIS INTERMEDIATE OLON SPA (IT) 2018-08-09 US claimed
EP-3328863-A1 PROCESS FOR THE PREPARATION OF IBRUTINIB AND NEW SYNTHESIS INTERMEDIATE OLON S.p.A. (IT) 2018-06-06 EP claimed
WO-2017017619-A1 PROCESS FOR THE PREPARATION OF IBRUTINIB AND NEW SYNTHESIS INTERMEDIATE OLON S.P.A. (IT) 2017-02-02 WO claimed
US-7671106-B2 Cap liners, closures and gaskets from multi-block polymers DOW GLOBAL TECHNOLOGIES INC. (US) 2010-03-02 US claimed
JP-2008545017-A 2008-12-11 JP claimed
EP-1877513-A2 CAP LINERS, CLOSURES AND GASKETS FROM MULTI-BLOCK POLYMERS Dow Global Technologies Inc. (US) 2008-01-16 EP claimed
WO-2006113000-A2 CAP LINERS, CLOSURES AND GASKETS FROM MULTI-BLOCK POLYMERS DOW GLOBAL TECHNOLOGIES INC. (US) 2006-10-26 WO claimed
US-20060199911-A1 Cap liners, closures and gaskets from multi-block polymers DOW GLOBAL TECHNOLOGIES INC. (US) 2006-09-07 US claimed
US-6617295-B2 Foaming or expansion of the resin brought about by molded particles of blowing agent, wax binder and filler enables the polymeric material to flow through the polymer processing machinery under lower pressures POLYONE CORPORATION 2003-09-09 US claimed
WO-1999035187-A1 REWORKABLE EPOXY UNDERFILL ENCAPSULANTS GEORGIA TECH RESEARCH CORPORATION (US) 1999-07-15 WO claimed
WO-1999025353-A1 THERAPEUTIC USES OF TRIAZOLO-PYRIDAZINE DERIVATIVES MERCK SHARP & DOHME LIMITED (GB) 1999-05-27 WO claimed
EP-0891390-A1 FOAMED GASKETS MADE FROM HOMOGENEOUS OLEFIN POLYMERS THE DOW CHEMICAL COMPANY (US) 1999-01-20 EP claimed
US-5723507-A ETHYLENE POLYMERS FOR GASKET SEALS THE DOW CHEMICAL COMPANY (US) 1998-03-03 US claimed
WO-1998005731-A1 GASKETS MADE FROM OLEFIN POLYMERS THE DOW CHEMICAL COMPANY (US) 1998-02-12 WO claimed
WO-1997033935-A1 FOAMED GASKETS MADE FROM HOMOGENEOUS OLEFIN POLYMERS THE DOW CHEMICAL COMPANY (US) 1997-09-18 WO claimed
US-5203793-A Conformable cushioning and stability device for articles of footwear LYDEN ROBERT M (US) 1993-04-20 US claimed
EP-0214552-B1 FOAMABLE MOLDINGS COMPOSITIONS MOBAY CORPORATION (US) 1990-09-26 EP claimed
US-4751250-A Process for foaming thermoplastic MOBAY CORPORATION (US) 1988-06-14 US claimed
US-4737523-A BLEND CONTAINING ANHYDRIDE-IMPACT RESISTANCE MOBAY CORPORATION (US) 1988-04-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180222909-A1 PROCESS FOR THE PREPARATION OF IBRUTINIB AND NEW SYNTHESIS INTERMEDIATE BTK, SYK, BCL6B TP53 384/4885MEN1 1203/4885KMT2A 674/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.