Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Iodoacetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodoacetic Acid SCHEMBL1700764 | 1.00 | FFAR3 (0.54) | — | |
| Iodoacetic Acid SCHEMBL4989126 | 0.88 | — | — | |
| Iodoacetic Acid SCHEMBL55098 | 0.88 | — | — | |
| Iodoacetic Acid SCHEMBL23152180 | 0.84 | — | — | |
| Iodoacetic Acid SCHEMBL3178383 | 0.84 | — | — | |
| Iodoacetic Acid SCHEMBL13741086 | 0.84 | — | — | |
| Iodoacetic Acid SCHEMBL4359681 | 0.84 | — | — | |
| Iodoacetic Acid SCHEMBL1083193 | 0.84 | — | — | |
| Iodoacetic Acid SCHEMBL3904173 | 0.84 | — | — | |
| Iodoacetic Acid SCHEMBL6909839 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117500786-A | TEAD inhibitors | 奥赖恩公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-105165823-A | Enhanced Retention Capabilities Through Methods Comprising Surface Treatment Of Functional Particulate Carrier Materials, And Functional Particulate Carrier Materials Made Therefrom | WORLD MINERALS INC | 2015-12-23 | — | — | CN | disclosed |
| EP-1572249-B1 | SOLID-PHASE FLUORINATION OF URACIL | HAMMERSMITH IMANET LTD (GB) | 2010-03-03 | — | — | EP | disclosed |
| US-7504208-B2 | Solid-phase fluorination of uracil and cytosine | HAMMERSMITH IMANET LIMITED (GB) | 2009-03-17 | — | — | US | disclosed |
| US-20060120958-A1 | Solid-phase fluorination of uracil and cytosine | HAMMERSMITH IMANET LIMITED (GB) | 2006-06-08 | — | — | US | disclosed |
| EP-1572249-A1 | SOLID-PHASE FLUORINATION OF URACIL AND CYTOSINE | Hammersmith Imanet Limited (GB) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004056400-A1 | SOLID-PHASE FLUORINATION OF URACIL AND CYTOSINE | HAMMERSMITH IMANET LIMITED (GB) | 2004-07-08 | — | — | WO | disclosed |