Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 7/20 | 0.40 |
| ▸ | CDK2 | P24941 | 6/20 | 0.40 |
| ▸ | NRAS | P01111 | 4/20 | 0.39 |
| ▸ | FLT3 | P36888 | 3/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.38 |
| ▸ | EHMT2 | Q96KQ7 | 4/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CDK7 | P50613 | 1/20 | 0.34 |
| ▸ | CCNH | P51946 | 1/20 | 0.34 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31639399 | 0.90 | CDK2 (0.37) | MAPKAPK2CDK2NRASFLT3IRAK4 | |
| SCHEMBL27327575 | 0.85 | NRAS (0.47) | MAPKAPK2CDK2NRASFLT3IRAK4 | |
| SCHEMBL27330143 | 0.85 | NRAS (0.47) | MAPKAPK2CDK2NRASFLT3IRAK4 | |
| SCHEMBL31639223 | 0.79 | KMT2A (0.43) | — | |
| SCHEMBL24542246 | 0.78 | NRAS (0.56) | MAPKAPK2CDK2NRASFLT3IRAK4 | |
| SCHEMBL27327398 | 0.78 | NRAS (0.48) | NRASFLT3IRAK4CHEK1BRD4 | |
| SCHEMBL27198198 | 0.78 | NRAS (0.56) | MAPKAPK2CDK2NRASFLT3IRAK4 | |
| SCHEMBL27330021 | 0.78 | NRAS (0.48) | NRASFLT3IRAK4CHEK1BRD4 | |
| SCHEMBL31639441 | 0.78 | SMPD3 (0.34) | — | |
| SCHEMBL27330138 | 0.77 | NRAS (0.49) | NRASFLT3IRAK4CHEK1CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025137567-A1 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2025-06-26 | — | — | WO | disclosed |