Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 14/20 | 0.33 |
| ▸ | IGF1R | P08069 | 3/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | NRAS | P01111 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.30 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.30 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31639540 | 1.00 | FYN (0.33) | FYNIGF1RKCNH2NRASFLT3 | |
| SCHEMBL31639342 | 0.81 | NRAS (0.44) | NRASFLT3 | |
| SCHEMBL31639345 | 0.77 | FYN (0.36) | FYNNRASFLT3 | |
| SCHEMBL30698331 | 0.76 | NRAS (0.40) | FYNNRASFLT3PDE4DDYRK3 | |
| SCHEMBL31739608 | 0.76 | NRAS (0.40) | FYNNRASFLT3PDE4DDYRK3 | |
| SCHEMBL24542495 | 0.72 | FLT3 (0.42) | FYNNRASFLT3PDE4DDYRK3 | |
| SCHEMBL29682761 | 0.72 | FLT3 (0.42) | FYNNRASFLT3PDE4DDYRK3 | |
| SCHEMBL31000221 | 0.72 | DYRK1A (0.38) | FYNPDE4DDYRK3CCNT1CDK9 | |
| SCHEMBL31639299 | 0.71 | KHK (0.34) | FYNNRASFLT3PDE4D | |
| SCHEMBL31000261 | 0.70 | IGF1R (0.38) | IGF1RKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025137567-A1 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2025-06-26 | — | — | WO | disclosed |