Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 5/20 | 0.43 |
| ▸ | NSD2 | O96028 | 2/20 | 0.42 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.35 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30698291 | 0.92 | PIK3CD (0.40) | PIK3CDNSD2EHMT2DNMT3APOLB | |
| SCHEMBL31639179 | 0.91 | PIK3CD (0.42) | PIK3CDNSD2EHMT2GPR119DNMT3A | |
| SCHEMBL31639286 | 0.89 | KMT2A (0.39) | PIK3CDNSD2DNMT3APOLBSCN9A | |
| SCHEMBL31639337 | 0.89 | PIK3CD (0.41) | PIK3CDNSD2EHMT2GPR119DNMT3A | |
| SCHEMBL31639188 | 0.88 | SCN9A (0.39) | PIK3CDNSD2DNMT3APOLBSCN9A | |
| SCHEMBL30698318 | 0.86 | PIK3CD (0.40) | PIK3CDNSD2DNMT3ASCN9ACFTR | |
| SCHEMBL31639332 | 0.81 | EGFR (0.38) | PIK3CDSCN9AKMT2A | |
| SCHEMBL31639111 | 0.81 | NRAS (0.38) | PIK3CDNSD2EHMT2DNMT3ACFTR | |
| SCHEMBL30698325 | 0.80 | NRAS (0.37) | PIK3CDNSD2EHMT2DNMT3ASCN9A | |
| SCHEMBL31639346 | 0.79 | PIK3CD (0.38) | PIK3CDNSD2EHMT2CFTRPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025137567-A1 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2025-06-26 | — | — | WO | disclosed |