SCHEMBL31639622

SCHEMBL31639622

CC(C)(C)OC(=O)N1CCN(c2c(F)cc(OC3CCC(=O)NC3=O)cc2F)CC1

nearest known ligand 0.57

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 16/20 0.57
▸ CRBN Q96SW2 16/20 0.57
▸ GPR119 Q8TDV5 3/20 0.41
▸ KDM4E B2RXH2 1/20 0.40
▸ MAPT P10636 1/20 0.40
▸ THRB P10828 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25168309 0.86 DDB1 (0.50) DDB1CRBNGPR119KDM4EMAPT
SCHEMBL31640567 0.84 DDB1 (0.58) DDB1CRBNGPR119KDM4EMAPT
SCHEMBL27036800 0.83 DDB1 (0.58) DDB1CRBNGPR119
SCHEMBL29744797 0.83 DDB1 (0.74) DDB1CRBNGPR119MAPT
SCHEMBL21903077 0.83 DDB1 (0.74) DDB1CRBNGPR119MAPT
SCHEMBL20595415 0.83 DDB1 (0.74) DDB1CRBNGPR119MAPT
SCHEMBL25269302 0.82 DDB1 (0.65) DDB1CRBNKDM4EMAPTTHRB
SCHEMBL31091747 0.82 DDB1 (0.65) DDB1CRBNGPR119MAPT
SCHEMBL31640077 0.82 DDB1 (0.55) DDB1CRBNGPR119KDM4EMAPT
SCHEMBL31313237 0.80 CRBN (0.50) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025137605-A1 COMPOUNDS FOR TARGETED DEGRADATION OF PROTO-ONCOGENE TYROSINE PROTEIN KINASE RECEPTOR C4 THERAPEUTICS, INC. (US) 2025-06-26 — — WO disclosed
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