Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 10/20 | 0.48 |
| ▸ | SRC | P12931 | 11/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 10/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 8/20 | 0.40 |
| ▸ | ABL1 | P00519 | 8/20 | 0.40 |
| ▸ | EGFR | P00533 | 8/20 | 0.40 |
| ▸ | HCK | P08631 | 8/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 8/20 | 0.40 |
| ▸ | MTOR | P42345 | 8/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 8/20 | 0.40 |
| ▸ | EPHB4 | P54760 | 8/20 | 0.40 |
| ▸ | PRKDC | P78527 | 8/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 6/20 | 0.40 |
| ▸ | JAK2 | O60674 | 2/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.39 |
| ▸ | LCK | P06239 | 2/20 | 0.39 |
| ▸ | FYN | P06241 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31639630 | 0.94 | RET (0.45) | RETSRCFGFR1KDRPIK3CD | |
| SCHEMBL31639568 | 0.87 | RET (0.43) | RETSRCFGFR1KDRPIK3CD | |
| Hydrochloric Acid SCHEMBL31640040 | 0.87 | RET (0.51) | RETSRCFGFR1KDRPIK3CD | |
| Hydrochloric Acid SCHEMBL31639825 | 0.86 | SRC (0.43) | RETSRCFGFR1KDRPIK3CD | |
| SCHEMBL31639349 | 0.85 | RET (0.56) | RETKDRHCKMAP2K2MAP2K1 | |
| Hydrochloric Acid SCHEMBL31639382 | 0.85 | RET (0.55) | RETKDRHCKMAP2K2MAP2K1 | |
| SCHEMBL31639311 | 0.84 | RET (0.40) | RET | |
| SCHEMBL31640306 | 0.84 | RET (0.42) | RET | |
| Hydrochloric Acid SCHEMBL31639440 | 0.83 | RET (0.42) | RET | |
| SCHEMBL31640331 | 0.82 | RET (0.42) | RETSRCFGFR1KDRPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025137605-A1 | COMPOUNDS FOR TARGETED DEGRADATION OF PROTO-ONCOGENE TYROSINE PROTEIN KINASE RECEPTOR | C4 THERAPEUTICS, INC. (US) | 2025-06-26 | — | — | WO | disclosed |