SCHEMBL31640243

SCHEMBL31640243

O=C1CCC(Nc2cc(F)c(C3CC4(CNC4)C3)c(F)c2)C(=O)N1

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 20/20 0.56
DDB1 Q16531 19/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL31640485 0.91 CRBN (0.47) CRBNDDB1
SCHEMBL23783198 0.86 CRBN (0.57) CRBNDDB1
Hydrochloric Acid SCHEMBL29094602 0.85 CRBN (0.56) CRBNDDB1
SCHEMBL24124590 0.84 CRBN (0.54) CRBNDDB1
SCHEMBL31639982 0.81 DDB1 (0.52) CRBNDDB1
SCHEMBL23551636 0.80 CRBN (0.62) CRBNDDB1
SCHEMBL31639925 0.78 CRBN (0.42) CRBNDDB1
SCHEMBL31639774 0.78 CRBN (0.53) CRBNDDB1
SCHEMBL23797593 0.77 DDB1 (0.50) CRBNDDB1
SCHEMBL25448648 0.77 DDB1 (0.50) CRBNDDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025137605-A1 COMPOUNDS FOR TARGETED DEGRADATION OF PROTO-ONCOGENE TYROSINE PROTEIN KINASE RECEPTOR C4 THERAPEUTICS, INC. (US) 2025-06-26 WO disclosed