Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31644710 | 0.82 | CYP3A4 (0.51) | CYP3A4TSHRTDP1ATMRECQL | |
| SCHEMBL31644757 | 0.80 | CYP3A4 (0.49) | CYP3A4TSHRTDP1ATMRECQL | |
| SCHEMBL31644838 | 0.78 | CYP3A4 (0.51) | CYP3A4TSHRTDP1ATMRECQL | |
| SCHEMBL31644959 | 0.76 | CYP3A4 (0.49) | CYP3A4TSHRTDP1ATMRECQL | |
| SCHEMBL21244612 | 0.76 | CYP3A4 (0.49) | CYP3A4TSHRTDP1ATMRECQL | |
| SCHEMBL9889024 | 0.73 | CYP3A4 (0.71) | CYP3A4TSHRTDP1ATMRECQL | |
| SCHEMBL9340238 | 0.73 | CYP3A4 (0.71) | CYP3A4TSHRTDP1ATMRECQL | |
| SCHEMBL44320 | 0.71 | CYP3A4 (0.89) | CYP3A4TSHRTDP1ATMRECQL | |
| Toluene SCHEMBL29287380 | 0.70 | CYP3A4 (0.66) | CYP3A4TSHRTDP1ATMRECQL | |
| SCHEMBL27423 | 0.69 | CYP3A4 (1.00) | CYP3A4TSHRTDP1ATMRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132542-A1 | MACROCYCLIC OREXIN AGONISTS | IDORSIA PHARMACEUTICALS LTD (CH) | 2025-06-26 | — | — | WO | disclosed |