Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MC4R | P32245 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.44 |
| ▸ | OGA | O60502 | 4/20 | 0.42 |
| ▸ | AURKA | O14965 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15332863 | 0.81 | HTR2A (0.58) | ALDH1A1KDM4EHTR2AHPGDMEN1 | |
| SCHEMBL31647228 | 0.79 | CYP2D6 (0.51) | CYP2D6ALDH1A1KDM4EHPGDMC4R | |
| SCHEMBL19461216 | 0.78 | OGA (0.71) | OGA | |
| SCHEMBL4994102 | 0.78 | HTR2A (0.58) | ALDH1A1KDM4EHTR2AHPGDMEN1 | |
| SCHEMBL31647002 | 0.76 | CYP2D6 (0.51) | CYP2D6ALDH1A1KDM4EHTR2AMEN1 | |
| SCHEMBL3366951 | 0.76 | HTR2A (0.53) | CYP2D6ALDH1A1KDM4EHTR2AHPGD | |
| SCHEMBL31646972 | 0.76 | OGA (0.64) | CYP2D6ALDH1A1KDM4EHPGDMC4R | |
| SCHEMBL31647041 | 0.75 | CYP2D6 (0.53) | CYP2D6ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL16226061 | 0.73 | CYP2D6 (1.00) | CYP2D6ALDH1A1HTR2ACYP1A2CYP3A4 | |
| SCHEMBL6706135 | 0.73 | CYP2D6 (1.00) | CYP2D6ALDH1A1HTR2ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025137146-A1 | SUBSTITUTED HETEROARYL ANALOGS AND USES THEREOF FOR THE TREATMENT OF HIV-ASSOCIATED NEUROCOGNITIVE DISORDERS | MOUKHA CHAFIQ OMAR (US) | 2025-06-26 | — | — | WO | disclosed |