Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 12/20 | 0.58 |
| ▸ | RAB9A | P51151 | 11/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.58 |
| ▸ | MEN1 | O00255 | 10/20 | 0.58 |
| ▸ | MAPT | P10636 | 8/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.58 |
| ▸ | HTT | P42858 | 6/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 8/20 | 0.53 |
| ▸ | POLB | P06746 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28427472 | 0.83 | NPC1 (0.48) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL31649420 | 0.83 | POLB (0.49) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL28427470 | 0.83 | NPC1 (0.48) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL31649115 | 0.83 | KMT2A (0.52) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL31649431 | 0.82 | POLB (0.46) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL31649308 | 0.82 | KMT2A (0.43) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL28433359 | 0.80 | KMT2A (0.61) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL28433360 | 0.80 | KMT2A (0.61) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL3993543 | 0.79 | KMT2A (0.51) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL3993540 | 0.79 | KMT2A (0.51) | NPC1RAB9AKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132831-A1 | N-HETEROARYL DERIVATIVES AND USES THEREOF FOR TREATING CANCER | UNIVERSITE D'AIX-MARSEILLE (FR) | 2025-06-26 | — | — | WO | claimed |
| WO-2025132831-A1 | N-HETEROARYL DERIVATIVES AND USES THEREOF FOR TREATING CANCER | UNIVERSITE D'AIX-MARSEILLE (FR) | 2025-06-26 | — | — | WO | disclosed |