Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 4/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649320 | 0.98 | NPSR1 (0.40) | MAOBNPSR1TSHRMEN1KMT2A | |
| SCHEMBL31649401 | 0.96 | NPSR1 (0.41) | MAOBNPSR1TSHRMEN1KMT2A | |
| SCHEMBL31649408 | 0.90 | MEN1 (0.41) | NPSR1TSHRMEN1KMT2APOLB | |
| SCHEMBL31649369 | 0.86 | TSHR (0.39) | NPSR1TSHRMEN1KMT2APOLB | |
| SCHEMBL31649351 | 0.85 | TSHR (0.39) | NPSR1TSHRMEN1KMT2APOLB | |
| SCHEMBL31649393 | 0.84 | TSHR (0.41) | NPSR1TSHRMEN1KMT2APOLB | |
| SCHEMBL31648994 | 0.84 | TSHR (0.40) | NPSR1TSHRMEN1KMT2APOLB | |
| SCHEMBL31649068 | 0.84 | F2 (0.43) | MEN1KMT2APOLBF2HTR1A | |
| SCHEMBL31649434 | 0.83 | TSHR (0.42) | NPSR1TSHRMEN1KMT2APOLB | |
| SCHEMBL31649370 | 0.83 | KMT2A (0.43) | NPSR1TSHRMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |