SCHEMBL31651383

SCHEMBL31651383

CCCOc1ccc(S(=O)(=O)N2CCC([C@H](O)CO[N+](=O)[O-])CC2)cc1-c1nc2c(CCC)cn(C)c2c(=O)[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ PDE5A O76074 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31651387 1.00 PDE5A (1.00) PDE5A
SCHEMBL20568172 1.00 PDE5A (1.00) PDE5A
SCHEMBL22028302 1.00 PDE5A (1.00) PDE5A
SCHEMBL20568461 1.00 PDE5A (1.00) PDE5A
SCHEMBL22065426 0.94 PDE5A (0.88) PDE5A
SCHEMBL20567816 0.92 PDE5A (1.00) PDE5A
SCHEMBL20570051 0.92 PDE5A (1.00) PDE5A
SCHEMBL22028288 0.92 PDE5A (1.00) PDE5A
SCHEMBL20568427 0.91 PDE5A (1.00) PDE5A
SCHEMBL22028316 0.91 PDE5A (0.84) PDE5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3630769-B1 NOVEL DUAL MODE OF ACTION SOLUBLE GUANYLATE CYCLASE ACTIVATORS AND PHOSPHODIESTERASE INHIBITORS AND USES THEREOF TOPADUR PHARMA AG (CH) 2025-07-02 — — EP claimed
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