Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 20/20 | 0.92 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20568085 | 1.00 | PDE5A (0.92) | PDE5A | |
| SCHEMBL20567811 | 0.96 | PDE5A (1.00) | PDE5A | |
| SCHEMBL20568425 | 0.96 | PDE5A (1.00) | PDE5A | |
| SCHEMBL20567812 | 0.94 | PDE5A (1.00) | PDE5A | |
| SCHEMBL31651380 | 0.94 | PDE5A (1.00) | PDE5A | |
| SCHEMBL22028304 | 0.92 | PDE5A (1.00) | PDE5A | |
| SCHEMBL20568055 | 0.90 | PDE5A (0.88) | PDE5A | |
| SCHEMBL6484518 | 0.90 | PDE5A (0.80) | PDE5A | |
| SCHEMBL6483207 | 0.90 | PDE5A (0.88) | PDE5A | |
| SCHEMBL22028351 | 0.90 | PDE5A (1.00) | PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3630769-B1 | NOVEL DUAL MODE OF ACTION SOLUBLE GUANYLATE CYCLASE ACTIVATORS AND PHOSPHODIESTERASE INHIBITORS AND USES THEREOF | TOPADUR PHARMA AG (CH) | 2025-07-02 | — | — | EP | claimed |