SCHEMBL31652475

SCHEMBL31652475

CC(C)CC1CCN(C(C(=O)N[C@H](CCCNC(=N)N)C(=O)NCc2ccc(O)cc2)c2ccccc2)CC1

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ NPY1R P25929 17/20 0.53
▸ NPY5R Q15761 4/20 0.49
▸ NPFFR1 Q9GZQ6 2/20 0.49
▸ NPFFR2 Q9Y5X5 2/20 0.49
▸ NPY4R P50391 6/20 0.46
▸ NPY2R P49146 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31652650 0.92 NPY1R (0.54) NPY1RNPY5RNPFFR1NPFFR2NPY4R
SCHEMBL31652837 0.91 NPY1R (0.55) NPY1RNPY5RNPFFR1NPFFR2
SCHEMBL31652734 0.91 NPY1R (0.55) NPY1RNPY5RNPFFR1NPFFR2
SCHEMBL31652820 0.91 NPY1R (0.54) NPY1RNPY5RNPFFR1NPFFR2NPY4R
SCHEMBL31652623 0.90 NPY1R (0.53) NPY1RNPY5RNPFFR1NPFFR2
SCHEMBL31652720 0.90 NPY1R (0.52) NPY1RNPY5RNPFFR1NPFFR2NPY4R
SCHEMBL31652652 0.88 NPY1R (0.51) NPY1RNPY5RNPFFR1NPFFR2NPY4R
SCHEMBL31652661 0.87 NPY1R (0.50) NPY1RNPY5RNPFFR1NPFFR2NPY4R
SCHEMBL31652535 0.87 NPY1R (0.54) NPY1RNPY5RNPFFR1NPFFR2NPY4R
SCHEMBL31652559 0.87 NPY1R (0.49) NPY1RNPY5RNPFFR1NPFFR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250213735-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. 2025-07-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250213735-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF NPY1R, NPY2R, NPY4R NPY1R 1/4885NPY5R 4/4885NPFFR1 21/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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