SCHEMBL31652831

SCHEMBL31652831

N=C(N)NCCC[C@@H](NC(=O)[C@H](c1ccccc1)N1Cc2ccccc2C1)C(=O)NCc1c(F)cc(O)cc1F

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ NPY1R P25929 13/20 0.41
▸ OPRM1 P35372 2/20 0.40
▸ NPY4R P50391 3/20 0.38
▸ NPY5R Q15761 3/20 0.38
▸ NPFFR1 Q9GZQ6 2/20 0.38
▸ NPFFR2 Q9Y5X5 2/20 0.38
▸ NPY2R P49146 1/20 0.38
▸ SCN5A Q14524 1/20 0.37
▸ SCN9A Q15858 1/20 0.37
▸ OPRD1 P41143 1/20 0.36
▸ OPRK1 P41145 1/20 0.36
▸ OPRL1 P41146 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31652432 0.87 NPY1R (0.45) NPY1RNPY4RNPY5RNPFFR1NPFFR2
SCHEMBL31652556 0.86 NPY1R (0.53) NPY1RNPY4RNPY5RNPFFR1NPFFR2
SCHEMBL31652905 0.86 NPY1R (0.53) NPY1RNPY4RNPY5RNPFFR1NPFFR2
SCHEMBL29299993 0.85 NPY1R (0.53) NPY1RNPY4RNPY5RNPFFR1NPFFR2
SCHEMBL31652448 0.85 NPY1R (0.45) NPY1RNPY4RNPY5RNPFFR1NPY2R
SCHEMBL31652910 0.85 NPY1R (0.45) NPY1RNPY4RNPY5RNPFFR1NPY2R
SCHEMBL31652727 0.80 NPY1R (0.40) NPY1RNPY4RNPY5RNPFFR1NPY2R
SCHEMBL29299989 0.80 NPY1R (0.50) NPY1RNPY4RNPY5RNPFFR1NPFFR2
SCHEMBL31652634 0.79 NPY1R (0.39) NPY1RNPY4RNPY5RNPFFR1NPY2R
SCHEMBL31652535 0.77 NPY1R (0.54) NPY1RNPY4RNPY5RNPFFR1NPFFR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250213735-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. 2025-07-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250213735-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF NPY1R, NPY2R, NPY4R NPY1R 1/4885OPRM1 254/4885NPY4R 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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