SCHEMBL31655772

SCHEMBL31655772

C#Cc1cccc2nc(Cn3nc(-c4ccc(O)cc4)c4c(N)ncnc43)n(Cc3ccccc3)c(=O)c12

nearest known ligand 0.73

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ PIK3CD O00329 20/20 0.73
▸ PIK3CG P48736 16/20 0.73
▸ PIK3R1 P27986 7/20 0.73
▸ PIK3CA P42336 7/20 0.53
▸ PIK3CB P42338 6/20 0.53
▸ PRKDC P78527 2/20 0.53
▸ ABL1 P00519 1/20 0.53
▸ SRC P12931 1/20 0.53
▸ MTOR P42345 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12116 1.00 PIK3CD (0.73) PIK3CDPIK3CGPIK3R1PIK3CAPIK3CB
SCHEMBL31655833 0.94 PIK3CD (0.71) PIK3CDPIK3CGPIK3R1PIK3CAPIK3CB
SCHEMBL11474 0.94 PIK3CD (0.71) PIK3CDPIK3CGPIK3R1PIK3CAPIK3CB
SCHEMBL31655822 0.93 PIK3CD (0.71) PIK3CDPIK3CGPIK3R1PIK3CAPIK3CB
SCHEMBL11397 0.93 PIK3CD (0.71) PIK3CDPIK3CGPIK3R1PIK3CAPIK3CB
SCHEMBL14696 0.93 PIK3CD (0.68) PIK3CDPIK3CGPIK3R1PIK3CAPIK3CB
SCHEMBL31655825 0.93 PIK3CD (0.68) PIK3CDPIK3CGPIK3R1PIK3CAPIK3CB
SCHEMBL11927932 0.93 PIK3CD (0.68) PIK3CDPIK3CGPIK3R1PIK3CAPIK3CB
SCHEMBL11725 0.92 PIK3CD (0.66) PIK3CDPIK3CGPIK3R1PIK3CAPIK3CB
SCHEMBL31655780 0.92 PIK3CD (0.66) PIK3CDPIK3CGPIK3R1PIK3CAPIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12350302-B2 Dosing regime and formulations for type B adenoviruses Akamis Bio Limited (GB) 2025-07-08 — — US disclosed
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