SCHEMBL31660185

SCHEMBL31660185

Oc1ccc(-c2noc(-c3ccccc3)n2)cc1O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H4 Q96RI1 3/20 0.65
RAB9A P51151 8/20 0.58
NPC1 O15118 6/20 0.58
NFKB1 P19838 3/20 0.58
NFKB2 Q00653 3/20 0.58
RELA Q04206 3/20 0.58
SMN1; SMN2 Q16637 10/20 0.57
TP53 P04637 6/20 0.57
MAPT P10636 5/20 0.57
HSD17B10 Q99714 4/20 0.57
KDM4E B2RXH2 3/20 0.57
ALDH1A1 P00352 3/20 0.57
MEN1 O00255 3/20 0.57
KMT2A Q03164 3/20 0.57
CHUK O15111 1/20 0.57
CASP3 P42574 1/20 0.57
TXNRD1 Q16881 1/20 0.57
SENP8 Q96LD8 1/20 0.57
SENP7 Q9BQF6 1/20 0.57
SENP6 Q9GZR1 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15425073 1.00 NR1H4 (0.65) NR1H4RAB9ANPC1NFKB1NFKB2
SCHEMBL8000260 0.90 SNCA (0.55) NR1H4RAB9ANPC1SMN1; SMN2TP53
Bromide SCHEMBL1660283 0.88 S1PR1 (0.54) NR1H4RAB9ANPC1SMN1; SMN2TP53
SCHEMBL31660373 0.83 TP53 (0.63) NR1H4RAB9ANPC1SMN1; SMN2TP53
SCHEMBL15425072 0.83 TP53 (0.63) NR1H4RAB9ANPC1SMN1; SMN2TP53
SCHEMBL17570197 0.82 NR1H4 (0.80) NR1H4RAB9ANPC1NFKB1NFKB2
SCHEMBL2063496 0.81 NR1H4 (0.67) NR1H4RAB9ANPC1NFKB1NFKB2
SCHEMBL3061782 0.81 NR1H4 (0.78) NR1H4RAB9ANPC1NFKB1NFKB2
SCHEMBL2062609 0.81 NR1H4 (0.78) NR1H4RAB9ANPC1NFKB1NFKB2
SCHEMBL321073 0.80 NR1H4 (0.91) NR1H4RAB9ANPC1NFKB1NFKB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250228242-A1 PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2025-07-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250228242-A1 PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL APP, APBA1, PRNP NR1H4 4814/4885RAB9A 1693/4885NPC1 2456/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.