Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 12/20 | 0.78 |
| ▸ | RAB9A | P51151 | 11/20 | 0.78 |
| ▸ | MAOA | P21397 | 1/20 | 0.69 |
| ▸ | BLVRB | P30043 | 1/20 | 0.69 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.55 |
| ▸ | RELA | Q04206 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26092403 | 1.00 | NPC1 (0.78) | NPC1RAB9AMAOABLVRBHDAC6 | |
| SCHEMBL60513 | 0.88 | NPC1 (0.77) | NPC1RAB9AMAOABLVRBHDAC6 | |
| SCHEMBL29607696 | 0.88 | NPC1 (0.77) | NPC1RAB9AMAOABLVRBHDAC6 | |
| SCHEMBL59495 | 0.87 | NPC1 (1.00) | NPC1RAB9AMAOABLVRBHDAC6 | |
| SCHEMBL30008519 | 0.87 | NPC1 (1.00) | NPC1RAB9AMAOABLVRBHDAC6 | |
| SCHEMBL26463350 | 0.87 | NPC1 (0.66) | NPC1RAB9AMAOABLVRBHDAC6 | |
| SCHEMBL12171227 | 0.87 | NPC1 (0.69) | NPC1RAB9AMAOABLVRBHDAC6 | |
| SCHEMBL60719 | 0.86 | NPC1 (0.72) | NPC1RAB9AMAOABLVRBHDAC6 | |
| SCHEMBL60102 | 0.86 | NPC1 (0.72) | NPC1RAB9AMAOABLVRBHDAC6 | |
| SCHEMBL60583 | 0.86 | NPC1 (0.72) | NPC1RAB9AMAOABLVRBHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250228242-A1 | PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2025-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250228242-A1 | PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL | APP, APBA1, PRNP | NPC1 2456/4885RAB9A 1693/4885MAOA 1118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.