Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30569112 | 0.79 | IRAK4 (0.44) | IRAK4GRM5 | |
| SCHEMBL29390315 | 0.77 | IRAK4 (0.40) | IRAK4GRM5 | |
| SCHEMBL24267834 | 0.77 | IRAK4 (0.40) | IRAK4GRM5 | |
| SCHEMBL26134334 | 0.77 | PLAUR (0.46) | IRAK4GRM5 | |
| SCHEMBL29714856 | 0.77 | KDM4E (0.67) | IRAK4 | |
| SCHEMBL5683198 | 0.77 | KDM4E (0.67) | IRAK4 | |
| SCHEMBL21090450 | 0.76 | KDM4E (0.50) | IRAK4GRM5 | |
| SCHEMBL30726441 | 0.75 | IRAK4 (0.47) | IRAK4 | |
| SCHEMBL16887703 | 0.70 | TP53 (0.43) | IRAK4 | |
| SCHEMBL10516257 | 0.69 | PLAUR (0.43) | IRAK4GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151728-A1 | LIGAND DIRECTED DEGRADER OF IRAK4 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-07-17 | — | — | WO | disclosed |
| WO-2025151602-A1 | HETEROARYL COMPOUNDS AS LIGAND DIRECTED DEGRADERS OF IRAK4 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-07-17 | — | — | WO | disclosed |