Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | PRPS1 | P60891 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8091551 | 0.90 | KMT2A (0.51) | KMT2AMEN1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL30233593 | 0.90 | KMT2A (0.51) | KMT2AMEN1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL17113145 | 0.82 | KMT2A (0.39) | KMT2AMEN1PRPS1LMNASMN1; SMN2 | |
| SCHEMBL15059343 | 0.82 | KRAS (0.48) | KMT2AMEN1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL29651126 | 0.82 | KMT2A (0.76) | KMT2AMEN1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL1746797 | 0.82 | KMT2A (0.76) | KMT2AMEN1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL31147905 | 0.81 | KMT2A (0.49) | KMT2AMEN1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL2010979 | 0.81 | MEN1 (0.41) | KMT2AMEN1SMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL22564665 | 0.81 | PDGFRA (0.41) | L3MBTL1 | |
| SCHEMBL29331361 | 0.81 | USP30 (0.42) | KMT2AMEN1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151602-A1 | HETEROARYL COMPOUNDS AS LIGAND DIRECTED DEGRADERS OF IRAK4 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-07-17 | — | — | WO | disclosed |