Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.49 |
| ▸ | GRM4 | Q14833 | 9/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.43 |
| ▸ | PDE2A | O00408 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL369077 | 0.91 | LRRK2 (0.50) | LRRK2GRM4PDE10A | |
| SCHEMBL16175277 | 0.82 | MALT1 (0.45) | LRRK2PDE10A | |
| SCHEMBL31441517 | 0.82 | LRRK2 (0.49) | LRRK2GRM4FFAR4 | |
| SCHEMBL2404646 | 0.82 | GRM4 (0.54) | LRRK2GRM4FFAR4 | |
| SCHEMBL15468354 | 0.82 | LRRK2 (0.55) | LRRK2GRM4PDE10AFFAR4GRM5 | |
| SCHEMBL2404642 | 0.82 | GRM4 (0.54) | LRRK2GRM4FFAR4 | |
| SCHEMBL31661296 | 0.82 | LRRK2 (0.49) | LRRK2GRM4FFAR4 | |
| SCHEMBL16333810 | 0.82 | LRRK2 (0.49) | LRRK2GRM4FFAR4 | |
| SCHEMBL2406994 | 0.82 | GRM4 (0.54) | LRRK2GRM4FFAR4 | |
| SCHEMBL366698 | 0.79 | LRRK2 (0.43) | LRRK2FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151517-A1 | THIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS ASSOCIATED WITH MISSFOLDING OF ALPHA-SYNUCLEIN PROTEIN | WAVEBREAK THERAPEUTICS LIMITED (US) | 2025-07-17 | — | — | WO | disclosed |