Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.54 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.54 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | AHR | P35869 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13593270 | 1.00 | MAPT (0.60) | MAPTSMN1; SMN2MAPK1RAB9ATP53 | |
| SCHEMBL14062901 | 0.83 | MAPT (0.67) | MAPTSMN1; SMN2MAPK1RAB9ATP53 | |
| SCHEMBL4347151 | 0.81 | MAPT (0.64) | MAPTSMN1; SMN2MAPK1RAB9ATP53 | |
| SCHEMBL14435720 | 0.81 | MAPT (0.64) | MAPTSMN1; SMN2MAPK1RAB9ATP53 | |
| SCHEMBL4428019 | 0.80 | MAPT (0.71) | MAPTSMN1; SMN2MAPK1RAB9ATP53 | |
| SCHEMBL28133927 | 0.80 | MAPT (0.70) | MAPTSMN1; SMN2MAPK1RAB9ATP53 | |
| SCHEMBL7636114 | 0.79 | MAPT (0.61) | MAPTSMN1; SMN2MAPK1RAB9ATP53 | |
| SCHEMBL2060705 | 0.78 | NR1H4 (0.73) | MAPTSMN1; SMN2MAPK1RAB9ATP53 | |
| SCHEMBL2721612 | 0.77 | MAPT (0.73) | MAPTSMN1; SMN2MAPK1RAB9ATP53 | |
| SCHEMBL2362772 | 0.77 | KMT2A (0.82) | MAPTSMN1; SMN2MAPK1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151884-A1 | USE OF GLYCOSAMINOGLYCAN SULFATED POLYSACCHARIDES SUCH AS SODIUM PENTOSAN POLYSULFATE IN COMBINATION WITH PERMEATION AGENTS TO TREAT ALZHEIMER'S DISEASE | PARSONS C LOWELL (US) | 2025-07-17 | — | — | WO | claimed |
| WO-2025151884-A1 | USE OF GLYCOSAMINOGLYCAN SULFATED POLYSACCHARIDES SUCH AS SODIUM PENTOSAN POLYSULFATE IN COMBINATION WITH PERMEATION AGENTS TO TREAT ALZHEIMER'S DISEASE | PARSONS C LOWELL (US) | 2025-07-17 | — | — | WO | disclosed |