Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCLC | P48506 | 1/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.61 |
| ▸ | GSR | P00390 | 2/20 | 0.54 |
| ▸ | GRM8 | O00222 | 1/20 | 0.54 |
| ▸ | GRM6 | O15303 | 1/20 | 0.54 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.54 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.54 |
| ▸ | GRM5 | P41594 | 1/20 | 0.54 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.54 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.54 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.54 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.54 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.54 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.54 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.54 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.54 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11739545 | 0.89 | GCLC (0.62) | GCLCPMP22GSRGRM8GRM6 | |
| SCHEMBL8707464 | 0.89 | GCLC (0.53) | GCLCPMP22GSRGRM8GRM6 | |
| SCHEMBL1157698 | 0.88 | GCLC (0.67) | GCLCPMP22GSRGRM8GRM6 | |
| SCHEMBL11735940 | 0.88 | GCLC (0.67) | GCLCPMP22GSRGRM8GRM6 | |
| SCHEMBL27926048 | 0.88 | GCLC (0.67) | GCLCPMP22GSRGRM8GRM6 | |
| SCHEMBL755869 | 0.85 | GCLC (0.59) | GCLCPMP22GSRGRM8GRM6 | |
| SCHEMBL11738674 | 0.85 | GCLC (0.59) | GCLCPMP22GSRGRM8GRM6 | |
| SCHEMBL27258367 | 0.82 | GCLC (0.47) | GCLCPMP22GSRGRM8GRM6 | |
| SCHEMBL7873489 | 0.82 | PMP22 (0.59) | GCLCPMP22GSRGRM8GRM6 | |
| SCHEMBL9193067 | 0.82 | PMP22 (0.59) | GCLCPMP22GSRGRM8GRM6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151884-A1 | USE OF GLYCOSAMINOGLYCAN SULFATED POLYSACCHARIDES SUCH AS SODIUM PENTOSAN POLYSULFATE IN COMBINATION WITH PERMEATION AGENTS TO TREAT ALZHEIMER'S DISEASE | PARSONS C LOWELL (US) | 2025-07-17 | — | — | WO | claimed |