Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2062605 | 1.00 | KDM4E (0.65) | KDM4EALDH1A1SMN1; SMN2TDP1ABCB1 | |
| SCHEMBL4399410 | 1.00 | KDM4E (0.65) | KDM4EALDH1A1SMN1; SMN2TDP1ABCB1 | |
| SCHEMBL31661824 | 1.00 | KDM4E (0.65) | KDM4EALDH1A1SMN1; SMN2TDP1ABCB1 | |
| SCHEMBL13348914 | 1.00 | KDM4E (0.65) | KDM4EALDH1A1SMN1; SMN2TDP1ABCB1 | |
| SCHEMBL4265430 | 0.99 | KDM4E (0.63) | KDM4EALDH1A1SMN1; SMN2TDP1ABCB1 | |
| SCHEMBL17443426 | 0.94 | KDM4E (0.69) | KDM4EALDH1A1SMN1; SMN2TDP1ABCB1 | |
| SCHEMBL5486254 | 0.91 | KDM4E (0.63) | KDM4EALDH1A1SMN1; SMN2TDP1ABCB1 | |
| SCHEMBL14396561 | 0.90 | POLB (0.63) | KDM4ESMN1; SMN2USP2TSHRPOLB | |
| Citric Acid SCHEMBL5495834 | 0.85 | KDM4E (0.59) | KDM4EALDH1A1SMN1; SMN2TDP1ABCB1 | |
| Citric Acid SCHEMBL1672548 | 0.85 | KDM4E (0.59) | KDM4EALDH1A1SMN1; SMN2TDP1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151884-A1 | USE OF GLYCOSAMINOGLYCAN SULFATED POLYSACCHARIDES SUCH AS SODIUM PENTOSAN POLYSULFATE IN COMBINATION WITH PERMEATION AGENTS TO TREAT ALZHEIMER'S DISEASE | PARSONS C LOWELL (US) | 2025-07-17 | — | — | WO | disclosed |