SCHEMBL31661839

SCHEMBL31661839

CCC(CC)Nc1c(Nc2cccc(C(=O)N3CCCC3)c2O)c(=O)c1=O

nearest known ligand 0.76

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CXCR2 P25025 19/20 0.76
CXCR1 P25024 7/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12086782 0.87 CXCR2 (1.00) CXCR2CXCR1
SCHEMBL31661832 0.86 CXCR2 (0.65) CXCR2CXCR1
SCHEMBL31661882 0.86 CXCR2 (0.65) CXCR2CXCR1
SCHEMBL12310920 0.83 CXCR2 (0.75) CXCR2CXCR1
SCHEMBL12263082 0.83 CXCR2 (0.73) CXCR2CXCR1
SCHEMBL12263119 0.83 CXCR2 (0.73) CXCR2CXCR1
SCHEMBL31661881 0.83 CXCR2 (0.76) CXCR2CXCR1
SCHEMBL31661885 0.83 CXCR2 (0.76) CXCR2CXCR1
SCHEMBL14896305 0.81 CXCR2 (0.63) CXCR2CXCR1
SCHEMBL14270864 0.81 CXCR2 (0.70) CXCR2CXCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025149577-A1 18F-CXCR2 PET TRACER JULIUS-MAXIMILIANS-UNIVERSITAET WUERZBURG (DE) 2025-07-17 WO disclosed