SCHEMBL31661845

SCHEMBL31661845

O=C(O)c1cccc(OCC2CCC2)c1

nearest known ligand 0.68

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NR1H4 Q96RI1 3/20 0.68
NR4A2 P43354 3/20 0.55
KMT2A Q03164 1/20 0.55
PARP15 Q460N3 3/20 0.54
PARP10 Q53GL7 3/20 0.54
PARP2 Q9UGN5 1/20 0.54
FABP1 P07148 1/20 0.52
DGAT1 O75907 2/20 0.51
CYP3A4 P08684 1/20 0.51
SOAT1 P35610 1/20 0.51
MAP4K4 O95819 1/20 0.50
POLB P06746 1/20 0.50
KAT6A Q92794 1/20 0.50
AKR1C3 P42330 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3069471 1.00 NR1H4 (0.68) NR1H4NR4A2KMT2APARP15PARP10
SCHEMBL30575478 0.97 NR1H4 (0.68) NR1H4NR4A2KMT2APARP15PARP10
SCHEMBL931299 0.97 NR1H4 (0.68) NR1H4NR4A2KMT2APARP15PARP10
SCHEMBL12420676 0.95 NR1H4 (0.67) NR1H4NR4A2KMT2APARP15PARP10
SCHEMBL30575482 0.95 NR1H4 (0.67) NR1H4NR4A2KMT2APARP15PARP10
SCHEMBL932137 0.95 NR1H4 (0.67) NR1H4NR4A2KMT2APARP15PARP10
SCHEMBL12420668 0.95 NR1H4 (0.67) NR1H4NR4A2KMT2APARP15PARP10
SCHEMBL3060401 0.94 NR1H4 (0.76) NR1H4NR4A2KMT2APARP15PARP10
SCHEMBL30281276 0.94 NR1H4 (0.76) NR1H4NR4A2KMT2APARP15PARP10
SCHEMBL12952742 0.89 NR1H4 (0.57) NR1H4NR4A2KMT2APARP15PARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025151884-A1 USE OF GLYCOSAMINOGLYCAN SULFATED POLYSACCHARIDES SUCH AS SODIUM PENTOSAN POLYSULFATE IN COMBINATION WITH PERMEATION AGENTS TO TREAT ALZHEIMER'S DISEASE PARSONS C LOWELL (US) 2025-07-17 WO claimed
WO-2025151884-A1 USE OF GLYCOSAMINOGLYCAN SULFATED POLYSACCHARIDES SUCH AS SODIUM PENTOSAN POLYSULFATE IN COMBINATION WITH PERMEATION AGENTS TO TREAT ALZHEIMER'S DISEASE PARSONS C LOWELL (US) 2025-07-17 WO disclosed