Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662014 | 0.92 | KRAS (0.42) | KRAS | |
| SCHEMBL31662485 | 0.83 | KRAS (0.47) | KRAS | |
| SCHEMBL31662352 | 0.80 | KRAS (0.40) | KRAS | |
| SCHEMBL26598179 | 0.79 | KRAS (0.44) | KRAS | |
| SCHEMBL31348395 | 0.79 | KRAS (0.44) | KRAS | |
| SCHEMBL27117610 | 0.78 | KRAS (0.48) | KRAS | |
| SCHEMBL31527192 | 0.76 | MAPK3 (0.46) | KRAS | |
| SCHEMBL30704222 | 0.76 | KRAS (0.44) | KRAS | |
| SCHEMBL26894941 | 0.76 | KRAS (0.44) | KRAS | |
| SCHEMBL25081130 | 0.76 | KRAS (0.45) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151594-A1 | FUSED AZINES AS RAS INHIBITORS AND METHODS OF USE THEREOF | KESTREL THERAPEUTICS INC. (US) | 2025-07-17 | — | — | WO | disclosed |