Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 17/20 | 0.55 |
| ▸ | MAPK3 | P27361 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662218 | 0.92 | KRAS (0.45) | KRASMAPK3MAPK1 | |
| SCHEMBL31662271 | 0.86 | KRAS (0.57) | KRASMAPK3MAPK1 | |
| SCHEMBL31662151 | 0.86 | KRAS (0.57) | KRASMAPK3MAPK1 | |
| SCHEMBL31662103 | 0.84 | KRAS (0.49) | KRASMAPK3MAPK1 | |
| SCHEMBL31662333 | 0.84 | KRAS (0.49) | KRASMAPK3MAPK1 | |
| SCHEMBL31662196 | 0.83 | KRAS (0.44) | KRAS | |
| SCHEMBL31527583 | 0.82 | MAPK3 (0.65) | KRASMAPK3MAPK1 | |
| SCHEMBL31527189 | 0.81 | MAPK3 (0.66) | KRASMAPK3MAPK1 | |
| SCHEMBL31662209 | 0.81 | KRAS (0.56) | KRASMAPK3MAPK1 | |
| SCHEMBL28906505 | 0.80 | KRAS (0.79) | KRASMAPK3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151594-A1 | FUSED AZINES AS RAS INHIBITORS AND METHODS OF USE THEREOF | KESTREL THERAPEUTICS INC. (US) | 2025-07-17 | — | — | WO | disclosed |