Desbromoarborescidine A

Desbromoarborescidine A

SCHEMBL31662855

c1ccc2c3c([nH]c2c1)[C@@H]1CCCCN1CC3

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 1/20 0.66
ADRA1A P35348 3/20 0.64
ADRA1D P25100 2/20 0.64
ADRA1B P35368 2/20 0.64
BRD3 Q15059 1/20 0.51
ADRA2A P08913 1/20 0.49
CYP2D6 P10635 3/20 0.49
HSD17B10 Q99714 2/20 0.49
ADRA2C P18825 1/20 0.49
TOP1 P11387 1/20 0.49
RB1 P06400 1/20 0.49
KDM4E B2RXH2 1/20 0.48
MEN1 O00255 1/20 0.48
USP2 O75604 1/20 0.48
CYP1A2 P05177 1/20 0.48
ALOX15 P16050 1/20 0.48
TSHR P16473 1/20 0.48
KMT2A Q03164 1/20 0.48
HIF1A Q16665 1/20 0.48
TDP1 Q9NUW8 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Desbromoarborescidine A SCHEMBL30363173 1.00 CHRNA7 (0.66) CHRNA7ADRA1AADRA1DADRA1BBRD3
Desbromoarborescidine A SCHEMBL29002756 1.00 CHRNA7 (0.66) CHRNA7ADRA1AADRA1DADRA1BBRD3
Desbromoarborescidine A SCHEMBL5269957 1.00 CHRNA7 (0.66) CHRNA7ADRA1AADRA1DADRA1BBRD3
SCHEMBL3859034 0.99 CHRNA7 (0.64) CHRNA7ADRA1AADRA1DADRA1BBRD3
SCHEMBL29458059 0.99 CHRNA7 (0.64) CHRNA7ADRA1AADRA1DADRA1BBRD3
SCHEMBL30363160 0.96 CHRNA7 (0.67) CHRNA7ADRA1AADRA1DADRA1BBRD3
SCHEMBL30363084 0.96 CHRNA7 (0.67) CHRNA7ADRA1AADRA1DADRA1BBRD3
SCHEMBL2887057 0.96 CHRNA7 (0.67) CHRNA7ADRA1AADRA1DADRA1BBRD3
Desbromoarborescidine A SCHEMBL30621266 0.92 CHRNA7 (0.58) CHRNA7ADRA1AADRA1DADRA1BBRD3
Arborescidine A SCHEMBL31069848 0.81 DHODH (0.50) CHRNA7ADRA1AADRA1DADRA1BADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025151874-A1 INDOLE ALKALOID ANTIPLASMODIAL AGENTS AND PREPARATION THEREOF UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) 2025-07-17 WO disclosed