Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.56 |
| ▸ | SCN4A | P35499 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | BCAT2 | O15382 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662985 | 0.76 | IDO1 (0.40) | IDO1SCN4AHPGDSPIM1NPC1 | |
| SCHEMBL13388290 | 0.75 | TRIM24 (0.46) | IDO1SCN4AMEN1LMNATHRB | |
| SCHEMBL1501845 | 0.72 | IDO1 (1.00) | IDO1SCN4AMEN1KMT2AHPGDS | |
| SCHEMBL29998937 | 0.72 | IDO1 (1.00) | IDO1SCN4AMEN1KMT2AHPGDS | |
| SCHEMBL31175932 | 0.72 | KMT2A (0.71) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL249552 | 0.72 | KMT2A (0.71) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL23350640 | 0.71 | IDO1 (0.62) | IDO1SCN4AMEN1LMNAKMT2A | |
| SCHEMBL2339759 | 0.71 | IDO1 (0.62) | IDO1SCN4AHPGDSPIM1NPC1 | |
| SCHEMBL21324986 | 0.71 | IDO1 (0.62) | IDO1SCN4AMEN1KMT2AHPGDS | |
| SCHEMBL29693625 | 0.71 | IDO1 (0.62) | IDO1SCN4AHPGDSPIM1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149498-A1 | BENZYLPIPERIDINE DERIVATIVES AS TRP4 ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |