Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 7/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9938875 | 0.93 | HPGD (0.56) | HPGDPTPN2PTPN1PTPN6RECQL | |
| SCHEMBL22051329 | 0.88 | HPGD (0.58) | HPGDPTPN2PTPN1PTPN6RECQL | |
| SCHEMBL21994463 | 0.85 | HPGD (0.57) | HPGDPTPN2PTPN1PTPN6RECQL | |
| SCHEMBL20012124 | 0.84 | KMT2A (0.55) | HPGDPTPN2PTPN1PTPN6RECQL | |
| SCHEMBL12440443 | 0.84 | HTT (0.53) | HPGDPTPN2PTPN1PTPN6RECQL | |
| SCHEMBL4657877 | 0.83 | HPGD (0.52) | HPGDPTPN2PTPN1PTPN6RECQL | |
| SCHEMBL4239798 | 0.82 | HPGD (0.57) | HPGDPTPN2PTPN1PTPN6RECQL | |
| SCHEMBL4243752 | 0.82 | KDM4E (0.49) | HPGDPTPN2PTPN1PTPN6RECQL | |
| SCHEMBL583783 | 0.81 | HPGD (0.52) | HPGDPTPN2PTPN1PTPN6RECQL | |
| SCHEMBL19022363 | 0.80 | HPGD (0.57) | HPGDPTPN2PTPN1PTPN6RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149628-A1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF NICOTINAMIDE N-METHYL TRANSFERASE | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |