Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | BPTF | Q12830 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16373725 | 0.75 | KDM4E (0.47) | KDM4EHPGDMEN1KMT2AMAPK1 | |
| SCHEMBL13523663 | 0.74 | KDM4E (0.59) | KDM4EHPGDMEN1KMT2AMAPK1 | |
| SCHEMBL17788549 | 0.73 | KDM4E (0.45) | KDM4EHPGDMEN1KMT2AMAPK1 | |
| SCHEMBL13153128 | 0.73 | KDM4E (0.63) | KDM4EHPGDMEN1KMT2AMAPK1 | |
| SCHEMBL18568567 | 0.71 | KDM4E (0.61) | KDM4EHPGDMEN1KMT2AMAPK1 | |
| SCHEMBL11710488 | 0.70 | KDM4E (0.59) | KDM4EHPGDMEN1KMT2AMAPK1 | |
| SCHEMBL6397072 | 0.69 | KDM4E (0.59) | KDM4EHPGDMEN1KMT2AMAPK1 | |
| SCHEMBL22161611 | 0.69 | KDM4E (0.59) | KDM4EHPGDMEN1KMT2AMAPK1 | |
| SCHEMBL10663924 | 0.69 | KDM4E (1.00) | KDM4EHPGDMEN1KMT2AMAPK1 | |
| SCHEMBL1586850 | 0.69 | KDM4E (0.53) | KDM4EHPGDMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149628-A1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF NICOTINAMIDE N-METHYL TRANSFERASE | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |