Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | STS | P08842 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31663336 | 0.84 | RECQL (0.44) | KMT2AMEN1STAT3HPGDGPR119 | |
| SCHEMBL31663205 | 0.72 | HTT (0.53) | HTTKDM4EMAPTTHRBKMT2A | |
| SCHEMBL31663054 | 0.71 | HTT (0.52) | HTTKDM4EMAPTTHRBKMT2A | |
| SCHEMBL31663414 | 0.70 | HTT (0.57) | HTTKDM4EMAPTTHRBKMT2A | |
| SCHEMBL20135048 | 0.69 | HTT (0.50) | HTTKDM4EMAPTTHRBKMT2A | |
| SCHEMBL31466315 | 0.68 | CNR1 (0.58) | HTTKDM4EMAPTTHRBKMT2A | |
| SCHEMBL20299835 | 0.68 | HTT (0.54) | HTTKDM4EMAPTTHRBKMT2A | |
| SCHEMBL1493280 | 0.68 | HTT (0.54) | HTTKDM4EMAPTTHRBKMT2A | |
| SCHEMBL15037238 | 0.67 | HTT (0.64) | HTTKDM4EMAPTTHRBKMT2A | |
| SCHEMBL30968724 | 0.67 | RECQL (0.45) | KDM4EMAPTTHRBKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149628-A1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF NICOTINAMIDE N-METHYL TRANSFERASE | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |