Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.62 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.62 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.60 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.60 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.53 |
| ▸ | GRM5 | P41594 | 1/20 | 0.53 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.50 |
| ▸ | TDO2 | P48775 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.49 |
| ▸ | TUBB | P07437 | 1/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14680957 | 0.83 | MKNK1 (0.63) | MKNK1MKNK2CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL8137336 | 0.82 | POLB (0.64) | MKNK1MKNK2CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL2659108 | 0.81 | MKNK1 (0.62) | MKNK1MKNK2CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL21076869 | 0.81 | MKNK1 (0.66) | MKNK1MKNK2CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL23326178 | 0.81 | CYP11B1 (0.62) | MKNK1MKNK2CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL29775352 | 0.81 | CYP11B1 (0.62) | MKNK1MKNK2CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL28225240 | 0.80 | MKNK1 (0.60) | MKNK1MKNK2CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL11425087 | 0.80 | CYP11B1 (0.55) | CYP11B1CYP11B2KCNH2GRM5GRIN2B | |
| SCHEMBL14694620 | 0.80 | CYP17A1 (0.67) | MKNK1MKNK2CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL6609680 | 0.80 | KCNH2 (0.53) | CYP11B1CYP11B2CYP3A4KCNH2GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3351533-B1 | BIARYL DERIVATIVE AND MEDICINE CONTAINING SAME | KAKEN PHARMA CO LTD (JP) | 2025-07-23 | — | — | EP | disclosed |