Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 5/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.70 |
| ▸ | TP53 | P04637 | 5/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22397344 | 1.00 | IDO1 (0.70) | IDO1KCNH2TP53THRBLMNA | |
| SCHEMBL31492901 | 0.90 | IDO1 (0.72) | IDO1KCNH2TP53THRBLMNA | |
| SCHEMBL22397417 | 0.90 | IDO1 (0.72) | IDO1KCNH2TP53THRBLMNA | |
| SCHEMBL22397378 | 0.85 | IDO1 (0.90) | IDO1KCNH2TP53THRBLMNA | |
| SCHEMBL31492881 | 0.85 | IDO1 (0.90) | IDO1KCNH2TP53THRBLMNA | |
| SCHEMBL22397373 | 0.83 | IDO1 (0.72) | IDO1KCNH2TP53THRBLMNA | |
| SCHEMBL31492770 | 0.83 | IDO1 (0.72) | IDO1KCNH2TP53THRBLMNA | |
| SCHEMBL22397379 | 0.82 | IDO1 (1.00) | IDO1KCNH2TP53THRBLMNA | |
| SCHEMBL22397618 | 0.82 | IDO1 (0.68) | IDO1KCNH2TP53THRBLMNA | |
| SCHEMBL31492851 | 0.82 | IDO1 (0.68) | IDO1KCNH2TP53THRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3703692-B1 | NOVEL SUBSTITUTED TETRAHYDROQUINOLIN COMPOUNDS AS INDOLEAMINE 2,3-DIOXYGENASE (IDO) INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2025-07-23 | — | — | EP | disclosed |