Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 16/20 | 0.54 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.54 |
| ▸ | DDB1 | Q16531 | 13/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | IKZF2 | Q9UKS7 | 2/20 | 0.45 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28505330 | 0.90 | CRBN (0.53) | CRBNGSPT1DDB1STAT3ALDH1A1 | |
| SCHEMBL21458925 | 0.88 | CRBN (0.54) | CRBNDDB1ALDH1A1CHRM2OPRM1 | |
| SCHEMBL28515726 | 0.88 | CRBN (0.54) | CRBNGSPT1DDB1STAT3ALDH1A1 | |
| SCHEMBL21069478 | 0.88 | CRBN (0.52) | CRBNGSPT1DDB1STAT3ALDH1A1 | |
| SCHEMBL30091370 | 0.87 | CRBN (0.52) | CRBNGSPT1DDB1STAT3 | |
| SCHEMBL21069391 | 0.87 | CRBN (0.53) | CRBNGSPT1DDB1STAT3ALDH1A1 | |
| SCHEMBL30850399 | 0.87 | CRBN (0.57) | CRBNGSPT1DDB1ALDH1A1CHRM2 | |
| SCHEMBL30850483 | 0.87 | CRBN (0.57) | CRBNGSPT1DDB1ALDH1A1CHRM2 | |
| SCHEMBL30850491 | 0.87 | CRBN (0.57) | CRBNGSPT1DDB1ALDH1A1CHRM2 | |
| SCHEMBL30850438 | 0.86 | CRBN (0.58) | CRBNGSPT1DDB1ALDH1A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3731869-B1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS INC (US) | 2025-07-23 | — | — | EP | disclosed |