SCHEMBL31664069

SCHEMBL31664069

CC(C)(C)OC(=O)N1CCC(OCC#Cc2ccnc3c2c2ccccc2n3C2CCC(=O)NC2=O)CC1

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 20/20 0.53
CRBN Q96SW2 20/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21070393 1.00 DDB1 (0.53) DDB1CRBN
SCHEMBL21996999 0.90 DDB1 (0.58) DDB1CRBN
SCHEMBL21069997 0.84 DDB1 (0.54) DDB1CRBN
SCHEMBL29612700 0.84 DDB1 (0.54) DDB1CRBN
SCHEMBL21106765 0.81 DDB1 (0.74) DDB1CRBN
SCHEMBL29612999 0.81 DDB1 (0.74) DDB1CRBN
SCHEMBL30036472 0.81 DDB1 (0.47) DDB1CRBN
SCHEMBL22776766 0.81 DDB1 (0.47) DDB1CRBN
SCHEMBL29079577 0.80 DDB1 (0.40) DDB1CRBN
SCHEMBL21997081 0.80 DDB1 (0.42) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3886904-B1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2026-04-22 EP disclosed
EP-4613773-A2 IRAK DEGRADERS AND USES THEREOF Kymera Therapeutics, Inc. (US) 2025-09-10 EP disclosed
EP-3731869-B1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2025-07-23 EP disclosed