Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 9/20 | 0.70 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.70 |
| ▸ | STAT3 | P40763 | 3/20 | 0.57 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.54 |
| ▸ | GRAMD1A | Q96CP6 | 5/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | PDE6D | O43924 | 1/20 | 0.49 |
| ▸ | BCL2 | P10415 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21069468 | 1.00 | CRBN (0.70) | CRBNDDB1STAT3DYRK2GRAMD1A | |
| SCHEMBL21069587 | 0.94 | CRBN (0.69) | CRBNDDB1STAT3DYRK2GRAMD1A | |
| SCHEMBL21070292 | 0.94 | CRBN (0.69) | CRBNDDB1STAT3DYRK2GRAMD1A | |
| SCHEMBL21071074 | 0.93 | CRBN (0.70) | CRBNDDB1STAT3DYRK2GRAMD1A | |
| SCHEMBL25189446 | 0.89 | CRBN (0.86) | CRBNDDB1STAT3DYRK2GRAMD1A | |
| SCHEMBL21069973 | 0.89 | CRBN (0.86) | CRBNDDB1STAT3DYRK2GRAMD1A | |
| SCHEMBL21106332 | 0.89 | CRBN (0.86) | CRBNDDB1STAT3DYRK2GRAMD1A | |
| SCHEMBL21759711 | 0.89 | CRBN (0.86) | CRBNDDB1STAT3DYRK2GRAMD1A | |
| SCHEMBL19503737 | 0.89 | CRBN (0.86) | CRBNDDB1STAT3DYRK2GRAMD1A | |
| SCHEMBL21070952 | 0.88 | CRBN (0.80) | CRBNDDB1STAT3DYRK2GRAMD1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4613773-A2 | IRAK DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2025-09-10 | — | — | EP | disclosed |
| EP-3731869-B1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS INC (US) | 2025-07-23 | — | — | EP | disclosed |