Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26923902 | 0.96 | TSHR (0.58) | TSHRL3MBTL1ZDHHC20RECQLSMN1; SMN2 | |
| SCHEMBL23853623 | 0.91 | TSHR (0.56) | TSHRL3MBTL1ZDHHC20EPHX2 | |
| SCHEMBL26923326 | 0.89 | TSHR (0.55) | TSHRL3MBTL1ZDHHC20SMN1; SMN2EPHX2 | |
| SCHEMBL13736171 | 0.85 | TSHR (0.48) | TSHRL3MBTL1SMN1; SMN2ALDH1A1TAAR1 | |
| SCHEMBL20840269 | 0.85 | TSHR (0.48) | TSHRL3MBTL1SMN1; SMN2ALDH1A1TAAR1 | |
| SCHEMBL998277 | 0.85 | TSHR (0.48) | TSHRL3MBTL1SMN1; SMN2ALDH1A1TAAR1 | |
| SCHEMBL13738486 | 0.85 | TSHR (0.48) | TSHRL3MBTL1SMN1; SMN2ALDH1A1TAAR1 | |
| SCHEMBL4173227 | 0.85 | TSHR (0.52) | TSHRL3MBTL1ZDHHC20SMN1; SMN2ALDH1A1 | |
| SCHEMBL26923742 | 0.84 | TSHR (0.39) | TSHRL3MBTL1RECQLMAPTHSD17B10 | |
| SCHEMBL8958187 | 0.82 | TSHR (0.41) | TSHRL3MBTL1RECQLMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3731869-B1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS INC (US) | 2025-07-23 | — | — | EP | disclosed |