Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 19/20 | 0.64 |
| ▸ | CCND1 | P24385 | 19/20 | 0.64 |
| ▸ | CCND2 | P30279 | 19/20 | 0.64 |
| ▸ | CCND3 | P30281 | 19/20 | 0.64 |
| ▸ | NUAK1 | O60285 | 2/20 | 0.63 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.63 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.63 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.63 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.63 |
| ▸ | MARK3 | P27448 | 1/20 | 0.62 |
| ▸ | MARK2 | Q7KZI7 | 1/20 | 0.62 |
| ▸ | MARK4 | Q96L34 | 1/20 | 0.62 |
| ▸ | NUAK2 | Q9H093 | 1/20 | 0.62 |
| ▸ | MARK1 | Q9P0L2 | 1/20 | 0.62 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.62 |
| ▸ | CDK1 | P06493 | 1/20 | 0.62 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.62 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.62 |
| ▸ | TTK | P33981 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31664324 | 0.85 | CDK4 (0.66) | CDK4CCND1CCND2CCND3NUAK1 | |
| SCHEMBL6942977 | 0.85 | CDK4 (0.66) | CDK4CCND1CCND2CCND3NUAK1 | |
| SCHEMBL6808315 | 0.85 | CDK4 (0.63) | CDK4CCND1CCND2CCND3FGFR1 | |
| SCHEMBL31664316 | 0.85 | CDK4 (0.67) | CDK4CCND1CCND2CCND3NUAK1 | |
| SCHEMBL31664303 | 0.85 | CDK4 (0.67) | CDK4CCND1CCND2CCND3NUAK1 | |
| SCHEMBL6939861 | 0.84 | CDK4 (0.66) | CDK4CCND1CCND2CCND3NUAK1 | |
| SCHEMBL31664314 | 0.83 | CDK4 (0.63) | CDK4CCND1CCND2CCND3NUAK1 | |
| SCHEMBL6941988 | 0.83 | CDK4 (0.65) | CDK4CCND1CCND2CCND3NUAK1 | |
| SCHEMBL6938878 | 0.82 | CDK4 (0.64) | CDK4CCND1CCND2CCND3NUAK1 | |
| SCHEMBL31664317 | 0.81 | CDK4 (0.63) | CDK4CCND1CCND2CCND3NUAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250388576-A1 | PYRIDONOPYRIMIDINE DERIVATIVE AS RSK INHIBITOR AND USE THEREOF | UNIV EAST CHINA NORMAL (CN) | 2025-12-25 | — | — | US | disclosed |
| EP-4588917-A1 | PYRIDONOPYRIMIDINE DERIVATIVE AS RSK INHIBITOR AND USE THEREOF | East China Normal University (CN) | 2025-07-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250388576-A1 | PYRIDONOPYRIMIDINE DERIVATIVE AS RSK INHIBITOR AND USE THEREOF | RPS6KA1, RPS6KA3, RPS6KA5 | CDK4 609/4885CCND1 2533/4885CCND2 3382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.