SCHEMBL316704

SCHEMBL316704

Cc1c(Br)ccc2c1OC(F)(F)C(F)(F)O2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3055306 0.85 ADORA2A (0.37)
SCHEMBL13138787 0.80 KDM4E (0.33)
SCHEMBL3908683 0.72 CETP (0.31)
SCHEMBL316804 0.69 PDE2A (0.34)
SCHEMBL7693244 0.68 HTR2C (0.33)
SCHEMBL12865263 0.64 AOC3 (0.50)
SCHEMBL12744378 0.64 ADORA2A (0.38)
SCHEMBL14007746 0.64 ADORA2A (0.44)
SCHEMBL21901486 0.63 ADORA2A (0.38)
SCHEMBL16043867 0.63 ADORA2A (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8093241-B2 Acid amide derivatives, process for their production and pesticides containing them ISHIHARA SANGYO KAISHA, LTD. (JP) 2012-01-10 US disclosed
US-20100093707-A1 ACID AMIDE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND PESTICIDES CONTAINING THEM ISHIHARA SANGYO KAISHA, LTD. (JP) 2010-04-15 US disclosed
US-7683096-B2 Acid amide derivatives, process for producing these, and pest control agent containing these ISHIHARA SANGYO KAISHA, LTD. (JP) 2010-03-23 US disclosed
US-20040254237-A1 Acid amide derivatives, process for producing these, and pest agent containing these ISHIHARA SANGYO KAISHA LTD. (JP) 2004-12-16 US disclosed
EP-1428817-A1 ACID AMIDE DERIVATIVES&amp;comma; PROCESS FOR PRODUCING THESE&amp;comma; AND PEST CONTROL AGENT CONTAINING THESE ISHIHARA SANGYO KAISHA, LTD. (JP) 2004-06-16 EP disclosed