Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 14/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16117855 | 1.00 | KRAS (0.46) | KRASHRH3KMT2ACXCR3KDM4E | |
| SCHEMBL16117856 | 0.84 | KRAS (0.65) | KRASCXCR3 | |
| SCHEMBL17807925 | 0.81 | KRAS (0.56) | KRAS | |
| SCHEMBL22035718 | 0.77 | KRAS (0.73) | KRAS | |
| SCHEMBL12605568 | 0.76 | KMT2A (0.56) | KMT2ACXCR3KDM4E | |
| SCHEMBL30642308 | 0.74 | KMT2A (0.55) | KRASKMT2AKDM4E | |
| SCHEMBL16117850 | 0.74 | KMT2A (0.55) | KRASKMT2AKDM4E | |
| SCHEMBL12605547 | 0.73 | GRIN2B (0.57) | KMT2AKDM4E | |
| SCHEMBL16897887 | 0.72 | KMT2A (0.52) | HRH3KMT2ACXCR3KDM4EOPRD1 | |
| SCHEMBL16897931 | 0.72 | KMT2A (0.52) | KMT2ACXCR3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE50527-E1 | Covalent inhibitors of KRAS G12C | ARAXES PHARMA LLC (US) | 2025-08-12 | — | — | US | disclosed |