Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.54 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31672496 | 0.91 | HDAC3 (0.55) | ALDH1A1KDM4ELMNAHDAC3HDAC4 | |
| SCHEMBL4658952 | 0.82 | KDM4E (0.59) | KDM4ELMNAHDAC3HDAC4HDAC1 | |
| SCHEMBL2781925 | 0.80 | KDM4E (0.61) | KDM4ELMNABLMHDAC3HDAC4 | |
| SCHEMBL10244791 | 0.79 | HDAC3 (0.61) | KDM4EHPGDLMNATSHRHDAC3 | |
| SCHEMBL4591341 | 0.76 | HDAC3 (0.58) | KDM4ELMNAHDAC3HDAC4HDAC1 | |
| SCHEMBL4591337 | 0.76 | HDAC3 (0.58) | KDM4ELMNAHDAC3HDAC4HDAC1 | |
| SCHEMBL29038556 | 0.76 | HDAC3 (0.67) | KDM4ELMNATSHRHDAC3HDAC4 | |
| SCHEMBL29038565 | 0.76 | HDAC3 (0.67) | KDM4ELMNATSHRHDAC3HDAC4 | |
| SCHEMBL542239 | 0.76 | TDP1 (0.74) | ALDH1A1KDM4EHPGDLMNASLC22A2 | |
| SCHEMBL13042362 | 0.76 | HDAC3 (0.57) | KDM4ELMNATSHRHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4599890-A2 | SUNITINIB FOR PREVENTING AND/OR TREATING AMYOTROPHIC LATERAL SCLEROSIS | Kyoto University (JP) | 2025-08-13 | — | — | EP | disclosed |