SCHEMBL3167336

SCHEMBL3167336

[CH2]C(=O)Cc1cccc2ccccc12

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.69
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
ATM Q13315 1/20 0.53
ACP3 P15309 1/20 0.52
L3MBTL1 Q9Y468 2/20 0.51
CYP1A2 P05177 2/20 0.50
KDM4E B2RXH2 1/20 0.50
LMNA P02545 1/20 0.50
HPGD P15428 1/20 0.50
PTGER4 P35408 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
BCHE P06276 1/20 0.50
CA12 O43570 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CA3 P07451 1/20 0.49
CA4 P22748 1/20 0.49
CA6 P23280 1/20 0.49
CA5A P35218 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30774302 0.83 TDP1 (0.74) TDP1MEN1KMT2AATMACP3
SCHEMBL7565966 0.83 TDP1 (0.74) TDP1MEN1KMT2AATMACP3
Formaldehyde SCHEMBL11102442 0.82 TDP1 (0.92) TDP1MEN1KMT2AATMACP3
SCHEMBL1200327 0.82 TDP1 (0.71) TDP1MEN1KMT2AATMACP3
SCHEMBL27599033 0.82 TDP1 (0.71) TDP1MEN1KMT2AATMACP3
SCHEMBL35925 0.82 TDP1 (1.00) TDP1MEN1KMT2AATMACP3
SCHEMBL29607554 0.82 TDP1 (1.00) TDP1MEN1KMT2AATMACP3
SCHEMBL27710793 0.82 TDP1 (1.00) TDP1MEN1KMT2AATMACP3
SCHEMBL1386762 0.80 TDP1 (0.69) TDP1MEN1KMT2AATMACP3
Ammonia Solution, Strong SCHEMBL22115500 0.80 TDP1 (0.96) TDP1MEN1KMT2AATMACP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102731387-B Salt for dye 住友化学株式会社 2016-08-03 CN disclosed
CN-102731387-A A salt for dye SUMITOMO CHEMICAL CO 2012-10-17 CN disclosed
CN-102161641-A Pyridone complex SUMITOMO CO LTD 2011-08-24 CN disclosed
CN-102134262-A Pyridine ketone complex SUMITOMO CO LTD 2011-07-27 CN disclosed
EP-1225480-B1 Radiation-sensitive resin composition JSR CORP (JP) 2010-03-17 EP disclosed
US-6838225-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2005-01-04 US disclosed
US-20020132181-A1 Radiation-sensitive resin composition JSR CORPORATION (JP) 2002-09-19 US disclosed
EP-1225480-A2 Radiation-sensitive resin composition JSR Corporation (JP) 2002-07-24 EP disclosed