Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 20/20 | 0.83 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23575446 | 0.85 | CSF1R (0.74) | CSF1RLRRK2 | |
| SCHEMBL30864154 | 0.84 | CSF1R (0.72) | CSF1RLRRK2 | |
| SCHEMBL4761193 | 0.84 | CSF1R (0.72) | CSF1RLRRK2 | |
| SCHEMBL23575454 | 0.81 | CSF1R (0.87) | CSF1RLRRK2 | |
| SCHEMBL13930258 | 0.80 | CSF1R (0.67) | CSF1RLRRK2 | |
| SCHEMBL2725168 | 0.79 | CSF1R (0.65) | CSF1R | |
| SCHEMBL5930114 | 0.78 | CSF1R (0.81) | CSF1R | |
| SCHEMBL23575595 | 0.78 | PDE4B (0.68) | CSF1R | |
| SCHEMBL23575811 | 0.78 | PDE4B (0.68) | CSF1R | |
| SCHEMBL23575743 | 0.77 | CSF1R (0.62) | CSF1RLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250255857-A1 | METHODS OF TREATING ANDROGEN RECEPTOR-INDEPENDENT PROSTATE CANCER | FOGHORN THERAPEUTICS INC. | 2025-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250255857-A1 | METHODS OF TREATING ANDROGEN RECEPTOR-INDEPENDENT PROSTATE CANCER | AR, ESRRB, ESRRA | CSF1R 2705/4885LRRK2 3365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.