SCHEMBL31679249

SCHEMBL31679249

Cc1cc(-c2cn3c(n2)sc2cc(C(=O)NCCCN4CCC(F)CC4)ccc23)ccn1

nearest known ligand 0.67

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 7/20 0.67
▸ TP53 P04637 4/20 0.64
▸ POLB P06746 1/20 0.63
▸ SMN1; SMN2 Q16637 1/20 0.63
▸ THRB P10828 2/20 0.62
▸ SLC2A1 P11166 1/20 0.59
▸ LMNA P02545 4/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24619434 0.88 MAPT (0.70) MAPTTP53POLBSMN1; SMN2THRB
SCHEMBL29925013 0.88 MAPT (0.70) MAPTTP53POLBSMN1; SMN2THRB
SCHEMBL29924922 0.87 MAPT (0.71) MAPTTP53POLBSMN1; SMN2THRB
SCHEMBL24619807 0.87 MAPT (0.71) MAPTTP53POLBSMN1; SMN2THRB
SCHEMBL31732405 0.87 MAPT (0.53) MAPTTP53POLBSMN1; SMN2THRB
SCHEMBL24619887 0.83 MAPT (0.61) MAPTTP53POLBSMN1; SMN2THRB
SCHEMBL29924991 0.83 MAPT (0.61) MAPTTP53POLBSMN1; SMN2THRB
SCHEMBL26992275 0.83 TP53 (0.66) MAPTTP53POLBSMN1; SMN2THRB
SCHEMBL24619524 0.82 MAPT (0.62) MAPTTP53POLBSMN1; SMN2THRB
SCHEMBL29924972 0.82 MAPT (0.62) MAPTTP53POLBSMN1; SMN2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12404283-B2 c-MYC mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-09-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12404283-B2 c-MYC mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 MAPT 3215/4885TP53 96/4885POLB 1476/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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