Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 19/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23303599 | 0.95 | BTK (0.46) | BTKLCKJAK2JAK1TYK2 | |
| Trifluoroacetic Acid SCHEMBL31679755 | 0.84 | BTK (0.41) | BTKLCK | |
| Trifluoroacetic Acid SCHEMBL31679714 | 0.84 | BTK (0.41) | BTKLCK | |
| Trifluoroacetic Acid SCHEMBL23303729 | 0.83 | BTK (0.38) | BTKJAK2JAK1TYK2 | |
| Trifluoroacetic Acid SCHEMBL23304011 | 0.83 | BTK (0.44) | BTKLCK | |
| SCHEMBL23303632 | 0.83 | BTK (0.49) | BTKLCK | |
| Trifluoroacetic Acid SCHEMBL31679722 | 0.82 | BTK (0.39) | BTKLCK | |
| Trifluoroacetic Acid SCHEMBL29840315 | 0.82 | BTK (0.40) | BTKLCK | |
| Trifluoroacetic Acid SCHEMBL31679761 | 0.81 | BTK (0.44) | BTKLCK | |
| SCHEMBL23303920 | 0.81 | BTK (0.56) | BTKLCKJAK2JAK1TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4051680-B1 | CONDENSED BI-HETEROCYCLES AS INHIBITING AGENTS FOR BRUTON'S TYROSINE KINASE | BIOGEN MA INC (US) | 2025-09-03 | — | — | EP | disclosed |